SAN FRANCISCO (AP) — Edwin Jackson became the first player in major league history to play for 14 teams when he made his Toronto Blue Jays debut and pitched five innings Wednesday in a 4-3 loss to the San Francisco Giants.

The 35-year-old right-hander allowed three runs — two earned — and six hits in five innings. He struck out two, walked one, hit a batter and left after 77 pitches with the score 3-3.

Brandon Crawford hit a tiebreaking home run in the sixth off Ryan Tepera (0-2).

Mark Melancon (1-0) pitched out of a first-and-third, no-outs jam in the sixth for the win. Will Smith struck out the side in the ninth to remain perfect in 11 save chances.

Toronto acquired Jackson from Oakland on Saturday for $30,000. He began his tenure with his new team by throwing an 88 mph cutter that Joe Panik took for a called strike.

Jackson had been tied with Octavio Dotel for most teams. Jackson agreed last month to a minor league contract with the A’s and was 1-0 with a 6.75 ERA in three minor league starts.

In addition to the Blue Jays and Athletics, Jackson has played for the Los Angeles Dodgers, Tampa Bay, Detroit, Arizona, the Chicago White Sox, St. Louis, Washington, the Chicago Cubs, Atlanta, Miami, San Diego and Baltimore.

Braves 4, Cardinals 0

ATLANTA (AP) — Austin Riley made a splash in his big league debut, homering off Michael Wacha to lead Atlanta over St. Louis.

Mike Soroka (4-1) pitched three-hit ball over seven scoreless innings.

The 22-year-old Riley was called up from Triple-A Gwinnett before the game after Ender Inciarte went on the 10-day injured list with a sore back. He struck out swinging in the first at-bat. Leading off the fourth, he launched a high fastball deep into the left-field seats, a 438-foot drive that gave the Braves a 2-0 lead. Riley hit another drive to the edge of the warning track his next time up.

Wacha (3-1) surrendered only four hits and one earned run over five innings.

Nationals 5, Mets 1

WASHINGTON (AP) — Patrick Corbin struck out 11 in eight strong innings and Victor Robles homered in Washington’s win over New York.

Anthony Rendon had three hits for Washington (17-25), which had lost seven of 10. He had two doubles and a single, scored twice and drove in a run.

Corbin (4-1) allowed one run and four hits to win his second consecutive start. He retired 15 of 16 batters from the third into the eighth inning.

Wilmer Font (1-1) gave up five runs and six hits — including a homer and three long doubles — in 2 1/3 innings.

J.D. Davis had an RBI double for the Mets, who had won three straight.

Diamondbacks 11, Pirates 1

PHOENIX (AP) — Zack Greinke pitched shutout ball into the eighth inning before exiting with abdominal tightness and Arizona routed Chris Archer and Pittsburgh.

Diamondbacks manager Torey Lovullo said Greinke would get an MRI on Friday.

Greinke (6-1) allowed four hits in 7 2-3 innings, then walked off the mound with a trainer with a 2-2 count on the Pirates’ Cole Tucker. Greinke struck out five, walked none.

Blake Swihart hit a two-run, inside-the-park home run in the eighth, and Eduardo Escobar and Adam Jones also homered for the Diamondbacks, who went 6-1 against the Pirates this season. Jarrod Dyson had two hits, scored three runs and stole two bases.

Melky Cabrera drove in the Pirates’ run with a two-out single in the ninth.

Pirates pitcher Chris Archer walked the bases loaded in the first inning, and all three runners scored. Archer (1-3) lasted just 3 2-3 innings, allowing six earned runs on four hits with four walks and a wild pitch.

Brewers 5, Phillies 2

PHILADELPHIA (AP) — Gio Gonzalez continued to make the most of his second stint in Milwaukee, allowing one run while pitching into the sixth inning in a win over Philadelphia.

Gonzalez (2-0) allowed seven hits, walked one and struck out three.

Jesus Aguilar ripped a two-run single off Jake Arrieta (4-4) in the third to give the Brewers a 4-1 lead and they hung on to take two of the first three games of a four-game set. Josh Hader tossed a scoreless ninth for his 11th save.

Bryce Harper lined a double to left field and made a sliding catch in right a day after he banged his left knee into the wall on a sliding catch. His double snapped an 0-for-15 slump.

Reds 6, Cubs 5

CINCINNATI (AP) — Eugenio Suarez hit a tying two-run homer in the eighth and slumping Yasiel Puig singled with the bases loaded in the 10th, rallying Cincinnati pasts Chicago.

The Cubs’ stingy bullpen let a solid start by Yu Darvish go to waste. Darvish allowed five hits, a pair of runs and fanned 11 batters, and Addison Russell hit a two-run homer to help the Cubs to a 5-3 lead.

Suarez’s homer off Carl Edwards Jr. tied it in the eighth, only the fourth time the Cubs have blown such a late lead.

Joey Votto drew a one-out walk from Brad Brach (3-1) in the 10th and Suarez followed with a single for his third hit of the game. After an intentional walk loaded the bases, Puig singled to the base of the wall in center, flipping his bat away in celebration.

Amir Garrett (3-1) pitched out of a two-on threat in the 10th.

Dodgers 2, Padres 0

LOS ANGELES (AP) — Kenta Maeda struck out 12 batters and drove in both runs as Los Angeles beat San Diego.

The right-hander gave up three hits in 6 2/3 innings and reached double-digit strikeouts for the fifth time in the majors. He finished one short of his career high for Ks set in 2016 against San Diego.

Maeda (5-2) also helped his own cause at the plate with two hits, including a two-out, two-run bloop single to right field in the second. He became the first Dodgers pitcher to have two hits and two RBIs in a game since Zack Greinke in 2014.

Corey Seager also had two hits for the Dodgers. Kenley Jansen worked the ninth for his 14th save.

Four Dodgers pitchers combined for a season-high 16 strikeouts.

Matt Strahm (1-3) went five innings and allowed two runs on seven hits. Eric Hosmer had three of San Diego’s four hits.

The Padres dropped four of five on their road trip and are 4-7 in their last 11 games overall.

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